COMBATING MOSQUITO BORNE DISEASES”- A brilliant idea for healthcare business in India
Healthcare industry in India has come a long way in terms of advancement.Although healthcare in India is showing a gradual progress, there are still millions of opportunities to create an evolving business by tackling the major challenges of the mass population.
With regard to mosquito-borne diseases, the world’s consideration has been focused on Zika for as far back as a year.
Be that as it may, different ailments like malaria or dengue still debilitate more individuals. Dengue and chikungunya are mosquito-borne ailments that are as of now re-rising as general wellbeing loads around the world. Every year, more than 390 million individuals are tainted with dengue, while chikungunya occasionally develops in exceedingly populated regions.
Mosquitoes transmit the causative specialists for a few irresistible maladies that can be destructive to people. The fast advancement of mosquitoes and their brisk reaction to changing conditions make mosquitoes a standout amongst the most troublesome creepy crawlies to balance.
“It is not the strongest of the species that survives, nor the most intelligent, but the one most responsive to change.” – Charles Darwin
Malaria is the most destructive parasitic illness spread by mosquitoes. Malaria is transmitted to people through bite of female Anopheles mosquitoes. The deadly parasite, Plasmodium, which is transmitted to people by the mosquito, incorporates high fever, serious cerebral pains, insanity, and perplexity. About 1 million malaria cases are accounted for every year in India. The majority of the malaria cases originate from six states- Orissa, Chhattisgarh, Jharkhand, Meghalaya, Arunachal Pradesh and Mizoram.
India has mapped out the arrangement to wipe out malaria by 2027 which is three years before the worldwide malaria disposal design of WHO- “WHO Global Technical Strategy for Malaria 2016– 2030”.
“Health care and education are too important NOT to be left to the free market.” ― Kevin D. Williamson
Sigtuple, a Bengaluru based startup in India is helping hospitals and healthcare centres improve the speed and accuracy of blood reports. They have developed AI-powered Manthana platform, which can analyze blood samples and generate medical reports in less than 10 minutes—and with complete accuracy. This Manthana platform is being used by a number of mid- to large-sized hospitals and diagnostics labs to catch Plasmodium, the parasite that causes malaria for early detection of Malaria.
“Give people what they need: food, medicine, clean air, pure water, trees and grass, pleasant homes to live in, some hours of work, more hours of leisure. Don’t ask who deserves it. Every human being deserves it.” ― Howard Zinn
Zika infection is spread by daytime-dynamic Aedes mosquitoe, a similar that spreads dengue and chikungunya.
It can cause a gentle sickness, with fever, rash, and joint agony. Be that as it may, disease amid pregnancy can prompt serious mind related birth deserts in babies. It is described by cerebrum harm and may cause different imperfections like visual impairment, deafness, and even seizures.
A few cases of Zika infection have been identified in India but India has no vaccine or cure for Zika virus infection.
European Patent Application EP3184118 relates to a recombinant vaccine against Zika virus. This patent was filed on 29th March 2016 by Themis Bioscience GmbH.
WIPO Patent Application WO/2017/142807, filed on 10th February 2017 by TAMIR BIOTECHNOLOGY, INC relates to treatment or prevention of Zika virus infections by administration of a ribonuclease.
United States Patent Application US20170216246, filed on 31st January 2017, by Lines, Thomas Christian pertains to a method for treating Zika virus infection with a composition containing quercetin or isoquercetin, together with one or more of vitamin B3, vitamin C, and a folate compound is described. Methods of preventing microcephaly and treating and preventing infections of other Flavivridae viruses are also described.
Indian startups have great energy, thought-process and leadership to tackle this challenge and come up with a system or method for detection and treatment of Zika virus infection.
DENGUE and CHIKUNGUNYA
The incidence of Mosquito borne diseases like Dengue and Chikungunya in has seen an upsurge over the past few years in India. Chikungunya and Dengue both spread through the bite of the Aedes aegypti mosquito..
Dengue is caused by one of four firmly related yet antigenically different flavivirus (DEN-1, DEN-2, DEN-3 and DEN-4). Symptoms include high fever, extreme frontal migraine, torment behind the eyes, muscle and joint torments, with or without measles-like rash and sickness which in extreme situation can cause hemorrhage and multi-organ failure.
“The world today has 6.8 billion people. That’s heading up to about nine billion. Now if we do a really great job on new vaccines, health care & reproductive health services, we could LOWER that by perhaps 10 or 15 percent.” ― Bill Gates
Sanofi Pasteur built up the world’s first dengue antibody, Dengvaxia®. It is a tetravalent dengue antibody, for the avoidance of infection caused by every one of the four dengue sorts in people from 9-45 years old living in endemic territories.
Symptoms of Chikungunya include- migraine, fever, weakness, queasiness, heaving, muscle torment and extreme joint torment. There is no vaccine available against Chikungunya in India and symptomatic treatment is utilized to treat throbs and fever. Chikungunya doesn’t kill yet causes extreme and agonizing appendage disfigurement that may last a long time.
“Our primary health care should begin on the farm and in our hearts, and not in some laboratory of the biotech and pharmaceutical companies.” ― Gary Hopkins
Bharat Biotech, a Hyderabad based company developed Chikungunya vaccine in India. The vaccine is in the early stage of human clinical trials.
Further, Sun Pharma will give its medication particles to National Institute of Virology (NIV), India to test on Zika, chikungunya, and dengue. The medications demonstrating promising outcomes will be taken further for business improvement.
Sun Pharma is focused on developing medications and antibodies against the rising circumstance of arboviruses comprehensively.
The joint effort of Sun Pharma and National Institute of Virology is in a state of harmony with the administration’s ‘Make in India’ activity. Together they plan to lead joint logical research and advancement to test drugs, biosimilars, antibodies and ailment control and end programs.
Sun Pharma inked another settlement with International Center for Genetic Engineering and Biotechnology (ICGEB) for the advancement of sheltered, powerful, and reasonable “Made in India” vaccine against dengue- DSV4. DSV4 is a recombinant Virus like Particle (VLPs) based vaccine.
Startups and budding entrepreneurs can come up with methods and devices that utilize robots or automation for early detection of mosquito-borne diseases.
Patents of some high priced drugs and vaccines are set to expire soon and some patents are already in the public domain. The development of biosimilars to these biologics can provide some affordable drugs for the treatment of these critical diseases. If you are a pharmaceutical business entity in India and want to explore the amazing field of utilizing expired patents in medicine sector contact us today to discuss your business goal with our team of Thinking Geeks.
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Aarti Dhillon is a third-year law student pursuing BBA LLB (Hons.) with specialization in corporate laws from the College of Legal Studies, University of Petroleum and Energy studies. She is an enthusiastic individual with an emphasis on achieving astounding standards both personally and academically. She is an aspiring corporate law and patent law enthusiast who is captivated with exploring, learning and practicing technology, invention, business, and law simultaneously. In her opinion Law, business and technology have reliably been the thing that has intrigued her the most and how with genuine learning and practice with regards to the said three, one can organize the framework to oblige individuals’ individual needs. She plans to have an effective law career ahead and apply her aptitudes obtained from both her work and academic experience and further enable her to make a difference in people’s life.